2879255-03-3

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2879255-03-3 Structure

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[Name] Antibacterial agent 169
[CAS] 2879255-03-3
[Synonyms] Antibacterial agent 169

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[Uses] Antibacterial agent 169 (Compound 28) is a pyrrolamide-type GyrB/ParE inhibitor with antibacterial activity. Antibacterial agent 169 has an inhibitory effect on Gyrase and Topo IV of Staphylococcus aureus, with IC50 values of 49 nmol/L and 1.513 μmol/L respectively[1].
[References] [1] Zhao X, et al. Discovery and druggability evaluation of pyrrolamide-type GyrB/ParE inhibitor against drug-resistant bacterial infection. Acta Pharm Sin B. 2023 Dec;13(12):4945-4962. DOI:10.1016/j.apsb.2023.08.030

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