| Identification | Back Directory | [Name]
(-)-2'''-O,3'''-O-Didemethyltyrosine [antibiotic] | [CAS]
79404-98-1 | [Synonyms]
YO-7625
Demethylmacrocin
Antibiotic YO-7625
(-)-2'''-O,3'''-O-Didemethyltyrosine [antibiotic] | [Molecular Formula]
C44H73NO17 | [MOL File]
79404-98-1.mol | [Molecular Weight]
888.047 |
| Hazard Information | Back Directory | [Uses]
Demethylmacrocin is a key intermediate in the biosynthetic pathway of Tylosin (HY-B0519A). Demethylmacrocin can be efficiently converted into tylosin through specific sequential oxidation and methylation reactions[1][2]. | [References]
[1] Kim E, et al. Characterization of the Two Methylation Steps Involved in the Biosynthesis of Mycinose in Tylosin. J Nat Prod. 2016 Aug 26;79(8):2014-21. DOI:10.1021/acs.jnatprod.6b00267
[2] Baltz RH, et al. Biosynthesis of the macrolide antibiotic tylosin. A preferred pathway from tylactone to tylosin. J Antibiot (Tokyo). 1983 Feb;36(2):131-41. DOI:10.7164/antibiotics.36.131 |
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