| Identification | Back Directory | [Name]
Urea, N-[(1S)-5-(1,1-dimethylethyl)-2,3-dihydro-1H-inden-1-yl]-N'-1H-indazol-4-yl- | [CAS]
808756-70-9 | [Synonyms]
(S)-ABT102
(S)-ABT 102, 10 mM in DMSO
(S)1(5(tertbutyl)2,3dihydro1Hinden1yl)3(1Hindazol4yl)urea
N-[(1S)-5-tert-butyl-2,3-dihydro-1H-inden-1-yl]-N'-1H-indazol-4-ylurea
Urea, N-[(1S)-5-(1,1-dimethylethyl)-2,3-dihydro-1H-inden-1-yl]-N'-1H-indazol-4-yl- | [Molecular Formula]
C21H24N4O | [MOL File]
808756-70-9.mol | [Molecular Weight]
348.44 |
| Hazard Information | Back Directory | [Uses]
(S)-ABT-102 is a TRPV1 Antagonist, with an IC50 of 123 nM. (S)-ABT-102 has analgesic activity[1]. | [References]
[1] Gomtsyan A, et al. Identification of (R)-1-(5-tert-butyl-2,3-dihydro-1H-inden-1-yl)-3-(1H-indazol-4-yl)urea (ABT-102) as a potent TRPV1 antagonist for pain management. J Med Chem. 2008 Feb 14;51(3):392-5. DOI:10.1021/jm701007g |
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