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1004316-18-0

基本信息

中文别名
可比司他 INT
可比西他中间体B碱
N-[(1R,4R)-4-氨基-5-苯基-1-(苄基)戊基]氨基甲酸 5-噻唑基甲基酯

应用领域

用途一
5-Thiazolylmethyl N-[(1R,4R)-4-Amino-5-phenyl-1-(phenylmethyl)pentyl]carbamate is an intermediate in the synthesis of 9-(Desmorpholinylethyl) 7,9-(1-Hydroxyethylene) Cobicistat (D296915), an impurity of Cobicistat (O849600), an HIV protease inhibitor and has been coadministered with low-dose ritonavir (R535000) as a pharmacoenhancer, significantly increasing their plasma concentrations.
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