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103213-49-6

中文名称 血纤维蛋白肽B
英文名称 GLU-GLY-VAL-ASN-ASP-ASN-GLU-GLU-GLY-PHE-PHE-SER-ALA-ARG
CAS 103213-49-6
分子式 C66H95N19O26
分子量 1570.57
MOL 文件 103213-49-6.mol
更新日期 2024/04/26 10:50:39
103213-49-6 结构式 103213-49-6 结构式

基本信息

中文别名
纤维蛋白肽B
[GLU1]-纤维蛋白肽B
[GLU1]-FIBRINOPEPTIDEB 人
人[GLU1] FIBRINOPEPTIDE B肽
英文别名
FGB
Fibrinogen beta chain
(GLU1)-FIBRINOPEPTIDE B
[GLU1]-FIBRINOPEPTIDE B HUMAN
[GLU1]-FIBRINOPEPTIDEB
Glu1]-Fibrinopeptide B human >=90% (HPLC)
Monoclonal Anti-FGB antibody produced in mouse
GLU-GLY-VAL-ASN-ASP-ASN-GLU-GLU-GLY-PHE-SER-ALA-ARG
GLU-GLY-VAL-ASN-ASP-ASN-GLU-GLU-GLY-PHE-PHE-SER-ALA-ARG
H-GLU-GLY-VAL-ASN-ASP-ASN-GLU-GLU-GLY-PHE-PHE-SER-ALA-ARG-OH
所属类别
生物:蛋白与多肽

物理化学性质

密度1.56±0.1 g/cm3(Predicted)
储存条件-20°C
酸度系数(pKa)3.33±0.10(Predicted)
形态粉末
水溶解性Soluble in water at 1mg/ml

安全数据

WGK Germany3
血纤维蛋白肽B价格(试剂级)
报价日期产品编号产品名称CAS号包装价格
2024/01/25HY-P0308血纤维蛋白肽B
[Glu1]-Fibrinopeptide B
103213-49-6500 μg1200元
2024/01/25HY-P0308血纤维蛋白肽B
[Glu1]-Fibrinopeptide B
103213-49-61mg1800元
2024/01/25HY-P0308血纤维蛋白肽B
[Glu1]-Fibrinopeptide B
103213-49-65mg7200元

常见问题列表

生物活性
[Glu1]-Fibrinopeptide B 衍生自纤维蛋白肽B氨基酸残基1-14。人纤维蛋白肽B(hFpB)是来自纤维蛋白原B β链的凝血酶衍生的蛋白水解裂解产物,可用于刺激中性粒细胞 (PMN),单核细胞和成纤维细胞。
体外研究

hFpB causes directed cell migration of PMN and fibroblasts that is optimal at approximately 10 nM. hFpB causes a rapid, dose-dependent increase in PMN cytoskeletal associated actin, but unlike fMLP, hFpB does not cause PMN aggregation, release of lysosomal enzymes (lysozyme and beta-glucuronidase), or the production of superoxide anion. These results suggest that hFpB may have a role in recruiting PMN and fibroblasts at sites of fibrin deposition and turnover. The capacity of hFpB to cause PMN chemotaxis without causing concurrent release of lysosomal enzymes or the production of superoxide anion is further evidence for the complexity of PMN responses to chemotactic agents.

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