108226-05-7
中文名称
108226-05-7
英文名称
Benzamide, 4-amino-5-chloro-2-propoxy-N-[1-[3-(tetrahydro-2-furanyl)propyl]-4-piperidinyl]-
CAS
108226-05-7
分子式
C22H34ClN3O3
分子量
423.98
MOL 文件
108226-05-7.mol
108226-05-7 结构式
基本信息
中文别名
化合物 T13570 英文别名
BENZAMIDE DERIVATIVE 1Benzamide, 4-amino-5-chloro-2-propoxy-N-[1-[3-(tetrahydro-2-furanyl)propyl]-4-piperidinyl]-
物理化学性质
沸点556.4±50.0 °C(Predicted)
密度1.20±0.1 g/cm3(Predicted)
储存条件-20°C储存
溶解度溶于二甲基亚砜
酸度系数(pKa)13.65±0.20(Predicted)
常见问题列表
生物活性
Benzamide Derivative 1 是来自专利 EP0213775A1，化合物 18，的苯甲酰胺衍生物。Benzamide Derivative 1 有潜力用于胃肠疾病的研究。靶点
Dopamine, mACh receptor
体外研究
Substituted benzamides have been shown to possess a number of pharmacological properties most of which are related to their ability to antagonize the central and peripheral effects of dopamine and/or facilitate the release of acetylcholine on to muscarinic receptors in the gastrointestinal smooth muscle. This has led to their successful clinical use as antiemetic and in the treatment of a wide range of gastrointestinal disorders of somatic, psychosomatic and iatrogenic origin.