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1118765-14-2

中文名称 O-去甲基阿哌沙班硫酸钠
英文名称 O-DesmethylApixabanSulphateNa
CAS 1118765-14-2
分子式 C24H23N5O7S
分子量 525.53
MOL 文件 1118765-14-2.mol
1118765-14-2 结构式 1118765-14-2 结构式

基本信息

中文别名
阿哌沙班杂质105
O-去甲基阿哌沙班硫酸钠
4,5,6,7-四氢-7-氧代-6-[4-(2-氧代-1-哌啶基)苯基]-1-[4-(磺氧基)苯基]-1H-吡唑并[3,4-C]吡啶-3-羧酰胺
英文别名
Apixaban Impurity 105
O-DesmethylApixabanSulphateNa
4,5,6,7-Tetrahydro-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1-[4-(sulfooxy)phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

应用领域

用途一
O-Desmethyl Apixaban Sulfate is an impurity of Apixaban (A726700), is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.
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