115044-69-4
中文名称
CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309)
英文名称
CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309)
CAS
115044-69-4
分子式
C103H185N31O24S
分子量
2273.83
MOL 文件
115044-69-4.mol
更新日期
2025/05/17 17:21:52
115044-69-4 结构式
基本信息
中文别名
CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309),LKKFNARRKLKGAILTTMLA 英文别名
LKKFNARRKLKGAILTTMLACAM KINASE II (290-309)
CALMODULIN BINDING DOMAIN
CALMODULIN DEPENDENT PROTEIN KINASE II
CaM Kinase II (290-309), Calmodulin Antagonist
CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309)
CALMODULIN-DEPENDENT PROTEIN KINASE IIFR AGMENT 290
CA2+/CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309)
CALMODULIN-DEPENDENT PROTEIN KINASE II FRAGMENT 290-309
Calmodulin Binding Domain - CAS 115044-69-4 - Calbiochem
CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309)价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2023/03/20 | HY-P1479 | CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309) Calmodulin-Dependent Protein Kinase II (290-309) | 115044-69-4 | 1 mg | 3300元 |
| 2023/03/20 | HY-P1479 | CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309) Calmodulin-Dependent Protein Kinase II (290-309) | 115044-69-4 | 5mg | 13000元 |
常见问题列表
生物活性
Calmodulin-Dependent Protein Kinase II (290-309) 是有效的 CaMK 拮抗剂， 抑制抑制Ca2+/钙调蛋白依赖性蛋白激酶II的 IC50 值为52 nM。靶点
IC50: 52 nM (calmodulin-dependent protein kinase II)
体外研究
Peptide 290 to 309 is found to be a potent calmodulin antagonist with an IC 50 of 52 nM for inhibition of Ca 2+ /calmodulin-dependent protein kinase. Neither truncation from the amino terminus (peptide 296-309) nor extension in the carboxyl-terminal direction (peptide 294-319) markedly affects calmodulin binding, whereas shortening the peptide from the carboxyl terminus (peptide 290-302) or from both ends (peptide 295-304) results in the elimination of this activity.