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1219089-77-6

中文名称 N2-Isobutyryl-O5′-(4,4′-dimethoxytrityl)-O2′-(1,1-dioxothiomorpholine-4-thiocarbonyl)guanosine O3′-(O-(2-cyanoethyl)-N,N-diisopropylphosphoramidite)
英文名称 N2-Isobutyryl-O5′-(4,4′-dimethoxytrityl)-O2′-(1,1-dioxothiomorpholine-4-thiocarbonyl)guanosine O3′-(O-(2-cyanoethyl)-N,N-diisopropylphosphoramidite)
CAS 1219089-77-6
分子式 C49H61N8O11PS2
分子量 1033.17
MOL 文件 1219089-77-6.mol
1219089-77-6 结构式 1219089-77-6 结构式

基本信息

英文别名
DMT-22O-TC-rG(ib) Phosphoramidite
DMT-2′O-TC-rG(ib) Phosphoramidite
DMT-2'O-TC-rG(ib) Phosphoramidite configured for ABI
N2-Isobutyryl-O5′-(4,4′-dimethoxytrityl)-O2′-(1,1-dioxothiomorpholine-4-thiocarbonyl)guanosine O3′-(O-(2-cyanoethyl)-N,N-diisopropylphosphoramidite)
Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-(2-methyl-1-oxopropyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] 2'-(1,1-dioxido-4-thiomorpholinecarbothioate)

物理化学性质

储存条件-20°C
溶解度acetonitrile: toluene (1:1): soluble0.1M at 18°C, clear (for 72h)
酸度系数(pKa)8.68±0.20(Predicted)
形态solid
颜色white to light yellow
InChIKeyLXUNLMGCWYNULU-NWGULGMGSA-N
SMILESCOc1ccc(cc1)C(OC[C@H]2O[C@H]([C@H](OC(=S)N3CCS(=O)(=O)CC3)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)n4cnc5C(=O)NC(NC(=O)C(C)C)=Nc45)(c6ccccc6)c7ccc(OC)cc7

安全数据

WGK Germany3
存储类别11 - Combustible Solids
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