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123852-10-8

中文名称 (1S,3R,4S,4AS,7S,8S,8AS)-4-氯-8-{2-[(2R,4R)-4-{[二甲基(2-甲基-2-丙基)硅烷基]氧基}-6-氧代四氢-2H-吡喃-2-基]乙基}-4A-羟基-3,7-二甲基-1,2,3,4,4A,7,8,8A-八氢-1-萘基2,2-二甲基丁酸酯
英文名称 2,2-Dimethylbutanoic Acid [1S-[1a,3a,4,4aa,7,8(2S*,4S*)]]-4-Chloro-8-[2-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]tetrahydro-6-oxo-2H-pyran-2-yl]ethyl]-1,2,3,4,4a,7,8,8a-octahydro-4a-hydroxy-3,7-dimethyl-1-naphthalenyl Ester
CAS 123852-10-8
分子式 C31H53ClO6Si
分子量 585.29
MOL 文件 123852-10-8.mol
123852-10-8 结构式 123852-10-8 结构式

基本信息

中文别名
(1S,3R,4S,4AS,7S,8S,8AS)-4-氯-8-{2-[(2R,4R)-4-{[二甲基(2-甲基-2-丙基)硅烷基]氧基}-6-氧代四氢-2H-吡喃-2-基]乙基}-4A-羟基-3,7-二甲基-1,2,3,4,4A,7,8,8A-八氢-1-萘基2,2-二甲基丁酸酯
英文别名
4-tert-Butyldimethylsilyl-5’-chloro-4a’-hydroxy Simvastatin
2,2-Dimethylbutanoic Acid [1S-[1a,3a,4,4aa,7,8(2S*,4S*)]]-4-Chloro-8-[2-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]tetrahydro-6-oxo-2H-pyran-2-yl]ethyl]-1,2,3,4,4a,7,8,8a-octahydro-4a-hydroxy-3,7-dimethyl-1-naphthalenyl Ester
2,2-DiMethylbutanoic Acid [1S-[1α,3α,4β,4aα,7β,8β(2S*,4S*)]]-4-Chloro-8-[2-[4-[[(1,1-DiMethylethyl)diMethylsilyl]oxy]tetrahydro-6-oxo-2H-pyran-2-yl]ethyl]-1,2,3,4,4a,7,8,8a-octahydro-4a-hydroxy-3,7-diMethyl-1-naphthalenyl Ester
Butanoic acid, 2,2-dimethyl-, 4-chloro-8-[2-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]tetrahydro-6-oxo-2H-pyran-2-yl]ethyl]-1,2,3,4,4a,7,8,8a-octahydro-4a-hydroxy-3,7-dimethyl-1-naphthalenyl ester, [1S-[1α,3α,4β,4aα,7β,8β(2S*,4S*)]]- (9CI)

物理化学性质

熔点49-51°C
沸点618.9±55.0 °C(Predicted)
密度1.09±0.1 g/cm3(Predicted)
储存条件吸湿性,-20℃冷冻,惰性气氛下
溶解度Chloroform, Dichloromethane, Ethyl Acetate, Methanol
酸度系数(pKa)12.94±0.70(Predicted)
形态Solid
颜色Off-White
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