1270138-41-4
中文名称
NSI-189磷酸盐
英文名称
NSI-189 Phosphate
CAS
1270138-41-4
分子式
C22H33N4O5P
分子量
464.495
MOL 文件
1270138-41-4.mol
更新日期
2024/12/23 09:09:17
1270138-41-4 结构式
基本信息
中文别名
NSI-189 磷酸NSI-189磷酸盐
英文别名
NSI-189 H3PO4NSI-189 phosphate
phosphoric acid/NSI-189 phosphate
(4-benzylpiperazin-1-yl)-[2-(3-methylbutylamino)pyridin-3-yl]methanone,phosphoric acid
所属类别
有机原料：羧酸类化合物及衍生物物理化学性质
形态Solid
颜色White to off-white
InChIKeyLWHMGALTTIYPJU-UHFFFAOYSA-N
SMILESP(O)(O)(O)=O.C(N1CCN(CC2=CC=CC=C2)CC1)(C1=CC=CN=C1NCCC(C)C)=O
应用领域
用途一
NSI-189 is a novel oral drug which was developed by Neuralstem for the treatment of cognitive disorders. Now the drug is being tested in phase II of clinical trials in patients suffering from major depressive disorder. The mechanism of NSI-189 action is explained by its ability to stimulate the generation of new neurons in the hippocampus, however the exact target molecule is still unknown.