129280-22-4
中文名称
129280-22-4
英文名称
Benzonitrile, 4-[2-(4,4-dimethyl-2-oxo-3-oxazolidinyl)-4-thiazolyl]-Methanesulfonamide, N-[4-[1-hydroxy-2-[[(1,2,3,4-tetrahydro-1-oxo-2-naphthalenyl)methyl]amino]ethyl]phenyl]-, hydrochloride
CAS
129280-22-4
分子式
C35H37ClN5O6S2
分子量
723.281
MOL 文件
129280-22-4.mol
129280-22-4 结构式
基本信息
中文别名
ANTI-HYPERTENSIVE SULFONANILIDE 1 英文别名
Anti-hypertensive sulfonanilide 1Benzonitrile, 4-[2-(4,4-dimethyl-2-oxo-3-oxazolidinyl)-4-thiazolyl]-Methanesulfonamide, N-[4-[1-hydroxy-2-[[(1,2,3,4-tetrahydro-1-oxo-2-naphthalenyl)methyl]amino]ethyl]phenyl]-, hydrochloride
常见问题列表
生物活性
Anti-hypertensive sulfonanilide 1是有效抗高血压剂，来自专利 EP0338793A2，化合物 XVIIIa,b*，实例1。体内研究
Anti-hypertensive sulfonanilide 1 can be classified as tetralin sulfonanilides, is found to have antihypertensive properties and is therefore useful in controlling elevated blood pressure in mammals such as humans. The effective antihypertensive amount for use will vary both with the route of administration, the condition under treatment and the mammal undergoing treatment, and is ultimately at the discretion of the physician. A suitable oral dose of the active compound for a mammal is in the range of from about 1 to about 50 mg per kilogram body weight per day; preferably from about 2 to about 20 mg/kg.