136112-01-1
英文名称
2-(hydroxymethyl)-4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl]phenol
CAS
136112-01-1
分子式
C50H68F3NO9S
MOL 文件
136112-01-1.mol
136112-01-1 结构式
基本信息
英文别名
AdoairSeretide
Advair Diskus
Adoair Diskus
Flutide Diskus
Seretide Accuhaler
SalMeterol-fluticasone propionate Mixt.
SalMeterol Fluticasone Propionate Mixture
[(6S,8S,10S,11S,13S,14S,16R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic Acid S-(FluoroMethyl) Ester Mixture with 4-Hydroxy-α1-[[[6-(4-phenylbutoxy)hexyl]aMino]Methyl]-1,3-benzenediMethanol
所属类别
化学试剂:芳香醇物理化学性质
InChIInChI=1S/C25H37NO4/c27-20-23-18-22(13-14-24(23)28)25(29)19-26-15-7-1-2-8-16-30-17-9-6-12-21-10-4-3-5-11-21/h3-5,10-11,13-14,18,25-29H,1-2,6-9,12,15-17,19-20H2
InChIKeyGIIZNNXWQWCKIB-UHFFFAOYSA-N
SMILESC1(O)=CC=C(C(O)CNCCCCCCOCCCCC2=CC=CC=C2)C=C1CO
应用领域
用途一
Salmeterol-fluticasone combination as Adoair, dry powder inhlaler/pressured metered-dose inhaler formulation for bronchial asthma, its benefit or demerits as device for inhalation drug delivery system in pharmacokinetics/pharmacodynamics at lung or peripheral bronchi, indications and usage of aerochamber, and clinical efficacy and safety in asthma control.