1374647-07-0

中文名称化合物 T24371

英文名称 L-Phenylalaninamide, N-[(2R,4R,5S)-5-[[(1,1-dimethylethoxy)carbonyl]amino]-4-hydroxy-1-oxo-6-phenyl-2-(phenylmethyl)hexyl]-L-leucyl-4-benzoyl-N-5-hexyn-1-yl-

CAS 1374647-07-0

分子式 C52H64N4O7

分子量 857.09

MOL 文件 1374647-07-0.mol

1374647-07-0 结构式

基本信息应用领域

基本信息

中文别名

化合物 T24371

英文别名

L458BPyne
L458-BPyne
L458 BPyne
L-Phenylalaninamide, N-[(2R,4R,5S)-5-[[(1,1-dimethylethoxy)carbonyl]amino]-4-hydroxy-1-oxo-6-phenyl-2-(phenylmethyl)hexyl]-L-leucyl-4-benzoyl-N-5-hexyn-1-yl-

应用领域

用途一

L458-BPyne is a γ-secretase modulator photoaffinity probe. It acts by identifying distinct allosteric binding sites on presenilin that can be exploited to reduce levels of pathogenic Aβ species.