13803-65-1

中文名称乳糖

英文名称 ANHYDROTETRACYCLINE HYDROCHLORIDE

CAS 13803-65-1

分子式 C22H23ClN2O7

分子量 462.88

MOL 文件 13803-65-1.mol

更新日期 2024/04/17 20:48:55

13803-65-1 结构式

基本信息物理化学性质安全数据常见问题列表

基本信息

中文别名

脱水四环素盐酸盐
脱水氯四环素盐酸盐
脱水四环素盐酸盐溶液,100PPM
(4S,4AS,12AS)-4-(DIMETHYLAMINO)-1,4,4A,5,12,12A-HEXAHYDRO-3,10,11,12A-TETRAHYDROXY-6-METHYL-1,12-DIOXO-2-NAPHTHACENECARBOXAMIDE 单盐酸盐

英文别名

AnhydrotetracyclineHCl
ANHYDROTETRACYCLINE HYDROCHLORIDE
5A,6-ANHYDROTETRACYCLINEHYDROCHLORIDE
Anhydrotetracycline hydrochloride ,97%
Anhydrotetracycline hydrochloride,'can be used as secondary standard.'
Anhydrotetracycline hydrochloride, 'can be used as a secondary standard'
(4S,4aS,12aS)-4-(DiMethylaMino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-Methyl-1,12-dioxo-2-naphthacenecarboxaMide Hydrochloride
(4S,4AS,12AS)-4-(DIMETHYLAMINO)-1,4,4A,5,12,12A-HEXAHYDRO-3,10,11,12A-TETRAHYDROXY-6-METHYL-1,12-DIOXO-2-NAPHTHACENECARBOXAMIDE MONOHYDROCHLORIDE
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-, monohydrochloride, (4S,4aS,12aS)-

所属类别

生物化工：双糖

物理化学性质

熔点223 °C

RTECS号QI7860000

储存条件Refrigerator

溶解度溶于乙醇、DMSO 或 DMF

形态粉末

颜色黄色至亮黄色

敏感性湿气敏感

BRN4228856

稳定性吸湿性

EPA化学物质信息2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-, hydrochloride (1:1), (4S,4aS,12aS)- (13803-65-1)

安全数据

危险性符号(GHS)

GHS07,GHS08

警示词警告

危险性描述H319-H361

防范说明P201-P202-P264b-P280i-P305+P351+P338-P308+P313-P403-P501c

危险品标志Xn

危险类别码63-36

安全说明36/37/39-26

WGK Germany3

海关编码29413020

常见问题列表

生物活性

Anhydrotetracycline hydrochloride 是一种四环素的生物合成前体，是一种有效的竞争性的四环素破坏酶 (tetracycline destructase enzymes) 广谱抑制剂。Anhydrotetracycline hydrochloride 是真核细胞中四环素控制的基因表达系统的效应子。

体外研究

Anhydrotetracycline hydrochloride inhibits Tet(50) (IC ₅₀ =210 μM),Tet(X) (IC ₅₀ =41 μM), Tet(X)_3 (IC ₅₀ =3 μM) degradations of tetracyclines. Anhydrotetracycline hydrochloride inhibits Tet(50) (IC ₅₀ =210 μM),Tet(X) (IC ₅₀ =75 μM), Tet(X)_3 (IC ₅₀ =26 μM) degradations of chlortetracycline. Anhydrotetracycline hydrochloride inhibits Tet(50) (IC ₅₀ =120 μM),Tet(X) (IC ₅₀ =41 μM), Tet(X)_3 (IC ₅₀ =7 μM) degradations of demeclocycline.
Anhydrotetracycline hydrochloride inhibits Tet(50) (IC ₅₀ =210 μM),Tet(X) (IC ₅₀ =41 μM), Tet(X)_3 (IC ₅₀ =3 μM) degradations of tetracyclines. Anhydrotetracycline hydrochloride inhibits Tet(50) (IC ₅₀ =210 μM),Tet(X) (IC ₅₀ =75 μM), Tet(X)_3 (IC ₅₀ =26 μM) degradations of chlortetracycline. Anhydrotetracycline hydrochloride inhibits Tet(50) (IC ₅₀ =120 μM),Tet(X) (IC ₅₀ =41 μM), Tet(X)_3 (IC ₅₀ =7 μM) degradations of demeclocycline.