1383478-94-1
中文名称
CYM 9484
英文名称
N-[4-[(DiMethylaMino)sulfonyl]phenyl]-4-(hydroxydiphenylMethyl)-1-piperidinecarbothioaMide
CAS
1383478-94-1
分子式
C27H31N3O3S2
分子量
509.68
MOL 文件
1383478-94-1.mol
1383478-94-1 结构式
基本信息
中文别名
化合物 T10921 英文别名
CYM 9484N-[4-[(DiMethylaMino)sulfonyl]phenyl]-4-(hydroxydiphenylMethyl)-1-piperidinecarbothioaMide
1-Piperidinecarbothioamide, N-[4-[(dimethylamino)sulfonyl]phenyl]-4-(hydroxydiphenylmethyl)-
CYM 9484价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/02/08 | HY-107735 | CYM 9484 CYM 9484 | 1383478-94-1 | 5mg | 350元 |
| 2025/02/08 | HY-107735 | CYM 9484 | 1383478-94-1 | 10 mM * 1 mLin DMSO | 392元 |
| 2025/02/08 | HY-107735 | CYM 9484 CYM 9484 | 1383478-94-1 | 10mg | 490元 |
常见问题列表
生物活性
CYM 9484 是一种选择性强效神经肽 Y (NPY) Y2 受体拮抗剂，IC50 值为 19 nM。靶点
|
NPYY 2 receptor 19 nM (IC 50 ) |
体外研究
SF-11 is a selective, brain-penetrant NPY Y2 receptor antagonist with an IC 50 value of 190 nM. Systematically explore the SAR of the hit molecule SF-11 that leads to the identification of selective and highly potent small molecule NPY Y2 receptor antagonist CYM 9484 (Compound 16). CYM 9484 is 10-fold more potent than the hit molecule SF-11. CYM 9484 is prepared by the coupling of α,α-diphenylpiperidino-4-methanol with a variety of aryl isothiocyanates.