138559-60-1
中文名称
AC-ARG-ARG-TRP-TRP-CYS-ARG- NH2
CAS
138559-60-1
分子式
C45H66N18O7S
分子量
1003.19
MOL 文件
138559-60-1.mol
138559-60-1 结构式
AC-ARG-ARG-TRP-TRP-CYS-ARG- NH2价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2026/06/05 | HY-125567 | AC-ARG-ARG-TRP-TRP-CYS-ARG- NH2 Antileukinate | 138559-60-1 | 500 μg | 2527元 |
常见问题列表
生物活性
Antileukinate 是一种六肽，是有效的 CXC 趋化因子受体 (CXCR) 抑制剂。Antileukinate 能抑制中性粒细胞趋化和活化。Antileukinate 可用于急性炎症和损伤的研究。体外研究
Antileukinate inhibits the binding of human eotaxin to human eosinophils with an IC
50
of 8.2 μM.
Antileukinate (10-100 μM; 2 hours) significantly suppresses eosinophil chemotaxis to human eotaxin.
体内研究
Antileukinate (52.63 mg/kg; s.c.) protectes mice against acute pancreatitis and associated lung injury.
Antileukinate (5mg/kg; s.c.) inhibits the interaction between murine eotaxin and murine eosinophil.
| Animal Model: | Swiss mice (20-25g) |
| Dosage: | 52.63 mg/kg |
| Administration: | Subcutaneous injection |
| Result: | Reduced pancreatic edema induced by Caerulein (50 μg/kg). |