1426174-41-5
中文名称
Ezetimibe-d4 -D-Glucuronide, >85%
英文名称
Ezetimibe-d4 -D-Glucuronide, >85%
CAS
1426174-41-5
分子式
C30H25D4F2NO9
分子量
589.574
MOL 文件
1426174-41-5.mol
更新日期
2025/06/11 16:41:56
1426174-41-5 结构式
基本信息
中文别名
依折麦布-D4Β-D-葡糖醛酸依泽替米贝-Β-D-葡萄糖醛酸苷-D4
化合物 EZETIMIBE-D4PHENOXY-D-GLUCURONIDE
英文别名
Sch 60663-d4Sch 58235-d4 Glucuronide
Ezetimibe glucuronide-D4
Ezetimibe β-D-glucuronide-D4
Ezetimibe-d4 Phenoxy Glucuronide
Ezetimibe-d4 -D-Glucuronide, >85%
Ezetimibe-d4 β-D-Glucuronide, >85%
Ezetimibe-d4 Beta-D-Glucuronide, >85%
Ezetimibe N-Phenyl-D4 Phenoxy Glucuronide
4-[(2S,3R)-1-(4-Fluorophenyl-d4)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxo-2-azetidinyl]phenyl-D-Glucopyranosiduronic Acid
物理化学性质
熔点140-150°C
储存条件-20°C冷冻
溶解度DMSO (Slightly, Sonicated), Methanol (Very Slightly), Water (Very Slightly)
形态Solid
颜色White to Pale Brown
稳定性吸湿性
常见问题列表
生物活性
Ezetimibe phenoxy glucuronide-D4 (Ezetimibe glucuronide-D4) 是 Ezetimibe phenoxy glucuronide 的氘代物。Ezetimibe phenoxy glucuronide 是 Ezetimibe 的活性代谢物，具有抗高脂蛋白血症效果。Ezetimibe 是有效的胆固醇吸收抑制剂。体内研究
After oral administration, Ezetimibe is absorbed in the small intestine and more than 80% of Ezetimibe metabolized to Ezetimibe Glucuronide.