1453116-06-7

中文名称化合物 NAPI2B INHIBITOR 15

英文名称 6,9,12,15,18,21-Hexaoxa-3-azadocosanoic acid, 22-[3-[[[3-[[(2E)-2-[[4-chloro-3-(trifluoromethyl)phenyl]methylene]hydrazinyl]carbonyl]-4,5,6,7-tetrahydro-6,6-dimethylbenzo[b]thien-2-yl]amino]carbonyl]phenyl]-3-(2-methoxyethyl)-

CAS 1453116-06-7

分子式 C44H58ClF3N4O11S

分子量 943.46

MOL 文件 1453116-06-7.mol

1453116-06-7 结构式

基本信息物理化学性质应用领域

基本信息

中文别名

化合物 NAPI2B INHIBITOR 15

英文别名

6,9,12,15,18,21-Hexaoxa-3-azadocosanoic acid, 22-[3-[[[3-[[(2E)-2-[[4-chloro-3-(trifluoromethyl)phenyl]methylene]hydrazinyl]carbonyl]-4,5,6,7-tetrahydro-6,6-dimethylbenzo[b]thien-2-yl]amino]carbonyl]phenyl]-3-(2-methoxyethyl)-

物理化学性质

密度1.30±0.1 g/cm3(Predicted)

酸度系数(pKa)2.18±0.10(Predicted)

应用领域

用途一

NaPi2b is primarily expressed in the small intestine, lungs, and testes and plays an important role in phosphate homeostasis. The inhibition of NaPi2b, responsible for intestinal phosphate absorption, is considered to reduce serum phosphate levels, making it a promising therapeutic approach for hyperphosphatemia