148470-19-3
中文名称
SUBSTANCE P TFA
英文名称
Substance P TFA
CAS
148470-19-3
分子式
C65H99F3N18O15S
分子量
1461.67
MOL 文件
148470-19-3.mol
148470-19-3 结构式
物理化学性质
储存条件-20°C储存
溶解度Water: 1 mg/ml
形态A lyophilized powder
颜色White to off-white
水溶解性Water: 100 mg/mL
序列Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2
SUBSTANCE P TFA价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/05/22 | HY-P0201A | SUBSTANCE P TFA Substance P TFA | 148470-19-3 | 1mg | 500元 |
| 2025/05/22 | HY-P0201A | SUBSTANCE P TFA Substance P TFA | 148470-19-3 | 5mg | 1100元 |
| 2025/05/22 | HY-P0201A | SUBSTANCE P TFA Substance P TFA | 148470-19-3 | 10mg | 2000元 |
常见问题列表
生物活性
Substance P TFA (Neurokinin P TFA) 是一种神经肽，在中枢神经系统中作为神经递质和神经调节剂。Substance P 的内源性受体是神经激肽1受体 (neurokinin 1 receptor，NK1R)。靶点
Neurokinin 1 receptor
体外研究
The neuropeptide substance P (SP) that are mediated by the neurokinin 1 receptor (NK1-R) desensitize and resensitize, which may be associated with NK1-R endocytosis and recycling. SP and the NK1-R are internalized into the same clathrin immunoreactive vesicles, and then sorted into different compartments. SP is intact at the cell surface and in early endosomes, but slowly degraded in perinuclear vesicles. SP induces clathrin-dependent internalization of the NK1-R. The SP/NK1-R complex dissociates in acidified endosomes. SP is degraded, whereas the NK1-R recycles to the cell surface. SP induces internalization of the NK1-R both in transfected epithelial cells.