153804-05-8
153804-05-8 结构式
基本信息
中文别名
普拉沙坦 英文别名
FW 7203PRATOSARTAN
4(3H)-Cycloheptimidazolone, 5,6,7,8-tetrahydro-2-propyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
物理化学性质
沸点692.9±65.0 °C(Predicted)
密度1.32±0.1 g/cm3(Predicted)
储存条件-20°C储存
溶解度溶于二甲基亚砜
酸度系数(pKa)4.15±0.10(Predicted)
常见问题列表
生物活性
Pratosartan 是一种选择性的血管紧张素 II 受体拮抗剂。靶点
angiotensin II receptor
体外研究
Pratosartan, which is an orally active angiotensin II (AII) antagonist, exhibiting selective and potent antagonistic activity to AT 1 subtype. Pratosartan is a new angiotensin II type 1 receptor blocker. Pratosartan is an effective and well tolerated antihypertensive drug, and may has beneficial effect on hypertensive patients with some metabolic disorders.