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1621717-95-0

中文名称 SPACE peptide
英文名称 SPACE peptide
CAS 1621717-95-0
分子式 C??H??N??O??S?
分子量 1090.15
MOL 文件 1621717-95-0.mol
1621717-95-0 结构式 1621717-95-0 结构式

基本信息

中文别名
SPACE肽
H-ALA-CYS-THR-GLY-SER-THR-GLN-HIS-GLN-CYS-GLY-OH(DISULFIDE BRIDGE:CYS2-CYS10)
英文别名
SPACE peptide
SPACE peptide,AC-TGSTQHQ-CG,Disulfide Bridge 2–10
所属类别
生物化工:多肽

物理化学性质

沸点1870.9±65.0 °C(Predicted)
密度1.54±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
酸度系数(pKa)3.57±0.10(Predicted)
形态Solid
颜色White to off-white
序列Ala-Cys-Thr-Gly-Ser-Thr-Gln-His-Gln-Cys-Gly (Disulfide bridge: Cys2-Cys10)
SPACE peptide价格(试剂级)
报价日期产品编号产品名称CAS号包装价格
2025/05/22HY-P0123SPACE peptide1621717-95-01 mg500元
2025/05/22HY-P0123SPACE peptide
SPACE peptide
1621717-95-05 mg1300元
2025/05/22HY-P0123SPACE peptide
SPACE peptide
1621717-95-010mg2100元

常见问题列表

生物活性
SPACE peptide 是一种皮肤穿透肽 (SPPs)。SPACE peptide 能增强大分子透明质酸的局部传递。
体外研究

SPACE peptide, when conjugates to cargoes such as small molecules and proteins, is able to facilitate their penetration across the stratum corneum into epidermis and dermis.
SPACE peptide also exhibits increased penetration into various cells including keratinocytes, fibroblasts, and endothelial cells, likely through a macropinocytosis pathway.
SPACE peptide enhances Cyclosporine A skin penetration, via a transcellular pathway, enhancing its partitioning into keratin-rich corneocytes through concurrent binding of SPACE with keratin and Cyclosporine A.

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