1638851-44-1
1638851-44-1 结构式
物理化学性质
沸点597.7±50.0 °C(Predicted)
密度1.43±0.1 g/cm3(Predicted)
酸度系数(pKa)12.54±0.70(Predicted)
形态Solid
颜色White to off-white
应用领域
用途一
HSK0935 is a potent and highly selective SGLT2 inhibitors (IC50 (hSGLT2) = 1.3 nM; IC50 (hSGLT1) + 1096nM). HSK0935 demonstrated excellent hSGLT2 inhibition of 1.3 nM and a high hSGLT1/hSGLT2 selectivity of 843-fold. It showed robust urinary glucose excretion in Sprague-Dawley (SD) rats and affected more urinary glucose excretion in Rhesus monkeys.