164323-42-6

中文名称 1,4A,4B,6,7,7A,8,13,13B,13C,14,15,15A,16A-十四氢-1,1,13B,13C-四甲基-3-(2-甲基-1-丙烯基)-5BH-[1,3]二恶英并[5'',4'':2',3']环氧乙烷并[4',4'A][1]苯并吡喃并[5',6':6,7]茚并[1,2-B]吲哚-5B-醇

英文名称 TERPENDOLE C

CAS 164323-42-6

分子式 C32H41NO5

分子量 519.67

MOL 文件 164323-42-6.mol

164323-42-6 结构式

基本信息应用领域

基本信息

中文别名

1,4A,4B,6,7,7A,8,13,13B,13C,14,15,15A,16A-十四氢-1,1,13B,13C-四甲基-3-(2-甲基-1-丙烯基)-5BH-[1,3]二恶英并[5'',4'':2',3']环氧乙烷并[4',4'A][1]苯并吡喃并[5',6':6,7]茚并[1,2-B]吲哚-5B-醇

英文别名

FO-2546-B
TERPENDOLE C
1,4a,4b,6,7,7a,8,13,13b,13c,14,15,15a,16a-Tetradecahydro-1,1,13b,13c-tetramethyl-3-(2-methyl-1-propenyl)-5bH-[1,3]dioxino[5'',4'':2',3']oxireno[4',4'a][1]benzopyrano[5',6':6,7]indeno[1,2-b]indol-5b-ol
5bH-[1,3]Dioxino[5'',4'':2',3']oxireno[4',4'a][1]benzopyrano[5',6':6,7]indeno[1,2-b]indol-5b-ol, 1,4a,4b,6,7,7a,8,13,13b,13c,14,15,15a,16a-tetradecahydro-1,1,13b,13c-tetramethyl-3-(2-methyl-1-propenyl)- (9CI)

应用领域

用途一

Acyl-coenzyme A:cholesterol acyltransferase (ACAT) isozymes are involved with cellular cholesterol esterification and regulate intestinal cholesterol absorption and hepatic lipoprotein secretion. Terpendole C inhibits ACAT1 and ACAT2 isozymes.