16670-83-0

中文名称 (+)-(2S,[2Α,6Α,11R])-1,2,3,4,5,6-六氢-6,11-二甲基-2,6-亚甲基-3-喷他佐辛-8-醇

英文名称 (+)-NORMETAZOCINE N-DEMETHYLATED ANALOG

CAS 16670-83-0

分子式 C14H19NO

分子量 217.31

MOL 文件 16670-83-0.mol

16670-83-0 结构式

基本信息物理化学性质应用领域安全数据

基本信息

中文别名

(+)-去甲美他佐辛
(+)-(2S,[2Α,6Α,11R])-1,2,3,4,5,6-六氢-6,11-二甲基-2,6-亚甲基-3-喷他佐辛-8-醇

英文别名

(+)-Normetazocine
(+)-NORMETAZOCINE N-DEMETHYLATED ANALOG
2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-, (2S,6S,11S)-
(+)-(2S,[2α,6α,11R])-1,2,3,4,5,6-Hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol

物理化学性质

熔点260-262 °C

沸点355.8±42.0 °C(Predicted)

密度1.088±0.06 g/cm3(Predicted)

酸度系数(pKa)9.79±0.60(Predicted)

形态neat

应用领域

用途1

(+)-Normetazocine is an analgesia-antagonistic active compound. It acts as both an agonist and antagonist, however shows less effects than (-)-Normetazocine (N721900). Used in the synthesis of BNIT, a selective inhibitor of the opioid receptor 蟽1.

安全数据

WGK Germany3