167006-13-5

中文名称化合物 T27743

英文名称 1-Cyclopentene-1-carboxylic acid, 2-[[[5-ethyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1,3,4-thiadiazol-2(3H)-ylidene]amino]carbonyl]-

CAS 167006-13-5

分子式 C25H23N7O3S

分子量 501.56

MOL 文件 167006-13-5.mol

167006-13-5 结构式

基本信息应用领域

基本信息

中文别名

化合物 T27743

英文别名

WK1492
WK-1492
WK14922K
WK-14922K
KRH-594 free acid
1-Cyclopentene-1-carboxylic acid, 2-[[[5-ethyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1,3,4-thiadiazol-2(3H)-ylidene]amino]carbonyl]-

应用领域

用途一

KRH-594, also known as WK-1492; WK-14922K, is a potent, specific and insurmountable AT1 receptor antagonist. KRH-594 prevents end-organ damage in stroke-prone spontaneously hypertensive/Izm rats. KRH-594 ameliorates nephropathy and hyperlipidaemia in diabetic spontaneously hypertensive rats.