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173401-47-3

中文名称 (3aS,4S,6aR)-4-(4-aminobutyl)tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one
英文名称 (3aS,4S,6aR)-4-(4-aminobutyl)tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one
CAS 173401-47-3
分子式 C9H17N3OS
分子量 215.32
MOL 文件 173401-47-3.mol
173401-47-3 结构式 173401-47-3 结构式

基本信息

中文别名
化合物 T19482
英文别名
Norbiotinamine
(3aS,4S,6aR)-4-(4-aminobutyl)tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one
1H-Thieno[3,4-d]imidazol-2(3H)-one, 4-(4-aminobutyl)tetrahydro-, (3aS,4S,6aR)-

物理化学性质

沸点478.0±30.0 °C(Predicted)
密度1.162±0.06 g/cm3(Predicted)
储存条件4°C, protect from light
溶解度H2O : 200 mg/mL (928.85 mM; ultrasonic and warming and heat to 60°C)
酸度系数(pKa)13.90±0.40(Predicted)
形态Solid
颜色White to off-white
(3aS,4S,6aR)-4-(4-aminobutyl)tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one价格(试剂级)
报价日期产品编号产品名称CAS号包装价格
2025/02/08HY-135717Norbiotinamine173401-47-31 mg1000元
2025/02/08HY-135717Norbiotinamine173401-47-35 mg2200元
2025/02/08HY-135717(3aS,4S,6aR)-4-(4-aminobutyl)tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one
Norbiotinamine
173401-47-310 mM * 1 mLin Water2369元

常见问题列表

生物活性
Norbiotinamine 是生物素的一种替代物。Norbiotinamine 可与氨基酸的羧基偶联得到具有反向连接的酰胺键的反向肽。
体外研究

In order to couple biotin to amino acids, reaction has to be with an amino group. An example is biocytin (biotin lysine). However, Norbiotinamine could be coupled with a carboxylic group of amino acids to give inverse peptides, having the amide linkage oriented in the opposite direction. As an example, Norbiotinamine is coupled with the NHS ester of N-Boc-glutamic acid γ-benzyl ester. The resulting norbiotinylamide of γglutamic acid (VII), obtained after deprotection, is similar to biocytin, but it has a shorter aliphatic chain and an inverted amide bond.

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