1781934-50-6
中文名称
AR-C102222 HYDROCHLORIDE
英文名称
AR-C102222 hydrochloride
CAS
1781934-50-6
分子式
C19H17ClF2N6O
分子量
418.83
MOL 文件
1781934-50-6.mol
1781934-50-6 结构式
AR-C102222 HYDROCHLORIDE价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/05/22 | HY-12122A | AR-C102222 HYDROCHLORIDE AR-C102222 hydrochloride | 1781934-50-6 | 5mg | 2800元 |
| 2025/05/22 | HY-12122A | AR-C102222 HYDROCHLORIDE AR-C102222 hydrochloride | 1781934-50-6 | 10 mM * 1 mLin DMSO | 3080元 |
| 2025/05/22 | HY-12122A | AR-C102222 HYDROCHLORIDE AR-C102222 hydrochloride | 1781934-50-6 | 10mg | 4500元 |
常见问题列表
生物活性
AR-C102222 hydrochloride 是一种有效的、竞争性的、有口服活性的、高度选择性的诱导型一氧化氮合酶 (iNOS) 抑制剂，IC50 值为 37 nM。AR-C102222 hydrochloride 具有镇痛和抗炎活性。体内研究
AR-C102222 (3, 10, 30, 100 mg/kg, P.O.) attenuates arachidonic acid-induced ear inflammation and possesses anti-inflammatory activity.
AR-C102222 shows good efficacy in a rat adjuvant-induced arthritis model.
| Animal Model: | Male Balb/c mice (20-25 g). |
| Dosage: | 3, 10, 30, 100 mg/kg. |
| Administration: | P.O. 55 min before the administration of 0.6% acetic acid (i.p., 1 mL/100 g volume). |
| Result: | Significantly inhibited arachidonic acid-induced ear inflammation following a dose of 100 mg/kg of has a maximal inhibition of approximately 79%. |