1797406-81-5
中文名称
1797406-81-5
英文名称
E3 ligase Ligand-Linker Conjugates 4
CAS
1797406-81-5
分子式
C32H47N7O8S
分子量
689.83
MOL 文件
1797406-81-5.mol
1797406-81-5 结构式
基本信息
中文别名
(S,R,S)-AHPC-四聚乙二醇-叠氮 英文别名
VH032-PEG4-N3VHL Ligand-Linker Conjugates 5
E3 ligase Ligand-Linker Conjugates 4
应用领域
用途一
UUN06815, also known as (S,R,S)-AHPC-PEG4-Azide, is a ProTAC building block. This conjugate contains a von Hippel-Lindau (VHL)-recruiting ligand, a linker with both hydrophobic and hydrophilic moieties, and a pendant azide for click chemistry with an alkyne on the target ligand. When used with other protein degrader building blocks with a pendant azide group, parallel synthesis can be used to more quickly generate ProTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand. This product has no formal name at the moment.