2056-98-6
中文名称
2'-脱氧胞苷三磷酸
英文名称
2'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE LITHIUM SALT
CAS
2056-98-6
分子式
C9H16N3O13P3
分子量
467.16
MOL 文件
2056-98-6.mol
2056-98-6 结构式
基本信息
中文别名
2'-脱氧胞苷三磷酸2'-脱氧胞苷 5'-三磷酸酯
((2R,3S,5R)-5-(4-氨基-2-氧代嘧啶-1(2H)-基)-3-羟基四氢呋喃-2-基)甲基四氢三磷酸
英文别名
5'-DCTPDCTP, LI
Deoxy-CTP
((2R,3S,5R)
DCTP LI-SALT
Deoxy-5'-CTP
dCTP.Free Acid
dCTP - 100mmol solution
deoxycytidine-triphosphate
2'-deoxycytidine triphosphate
所属类别
生物化工：核苷酸及其类似物物理化学性质
沸点811.5±75.0 °C(Predicted)
密度2.38±0.1 g/cm3(Predicted)
储存条件Sealed in dry,Room Temperature
酸度系数(pKa)0.80±0.50(Predicted)
形态水溶液稳定
水溶解性Water : ≥ 35 mg/mL (74.92 mM)
常见问题列表
生物活性
Deoxycytidine triphosphate (dCTP) 是可用于 DNA 合成 (DNA synthesis) 的核苷三磷酸。Deoxycytidine triphosphate 可用于实时 PCR，cDNA 合成 和 DNA 测序等研究。靶点
|
Human Endogenous Metabolite
|
体外研究
Assays of thirteen cell lines, derived from mouse lymphomas, myelomas, myeloid tumors, and a mastocytoma, for sensitivity to growth inhibition by 1-β-D-arabinofuranosylcytosine (ara-C) revealed a spectrum between the most and least sensitive which differed 100-fold from each other. An inverse correlation between sensitivity and cellular Deoxycytidine triphosphate (2′-Deoxycytidine-5′-triphosphate, dCTP) content is found, and this suggested that sensitivity of cells might be increased if the dCTP content was lowered during cell exposure to ara-C.
Deoxycytidine triphosphate trisodium salt is a phosphoethanolamine cytidylyltransferase substrate.