2086688-98-2
中文名称
保护基团-氨基氧基-五聚乙二醇-丙炔
英文名称
t-Boc-aminooxy-PEG5-propargyl
CAS
2086688-98-2
分子式
C18H33NO8
分子量
391.46
MOL 文件
2086688-98-2.mol
2086688-98-2 结构式
基本信息
中文别名
保护基团-氨基氧基-五聚乙二醇-丙炔 英文别名
Boc-NH-O-PEG5-PropargylBoc-aminooxy-PEG5-propargyl
t-Boc-aminooxy-PEG5-propargyl
3,6,9,12,15,18-Hexaoxa-2-azaheneicos-20-ynoic acid, 1,1-dimethylethyl ester
应用领域
用途一
t-Boc-aminooxy-PEG5-propargyl is a click crosslinker. Propargyl group is reactive with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. T-Boc-aminooxy can be converted to free aminooxy under mild acidic conditions and then can react with an aldehyde or ketone. The hydrophilic PEG spacer increases solubility in aqueous media.