2112737-93-4
中文名称
DSPE-PEG5-PROPARGL
英文名称
DSPE-PEG5-propargyl
CAS
2112737-93-4
分子式
C55H104NO14P
分子量
1034.39
MOL 文件
2112737-93-4.mol
2112737-93-4 结构式
基本信息
中文别名
DSPE-五聚乙二醇-丙炔磷脂-四聚乙二醇-炔基,DSPE-PEG5-PROPARGYL
英文别名
DSPE-PEG5-propargDSPE-PEG5-propargl
DSPE-PEG5-propargyl
Octadecanoic acid, (2R)-5-hydroxy-5-oxido-10-oxo-2-[(1-oxooctadecyl)oxy]-4,6,13,16,19,22,25-heptaoxa-9-aza-5-phosphaoctacos-27-yn-1-yl ester
所属类别
催化剂及助剂：聚合物应用领域
用途一
DSPE-PEG8-propargyl is a PEG linker with attached DSPE and propargyl groups. The DSPE-PEGs have been FDA approved for medical applications. The hydrophobic properties of the DSPE allow for the encapsulation and congregation of other hydrophobic drugs. The hydrophilic PEG linker increases the water solubility of the overall compound allowing for the delivery of the drug. The hydrophilic PEG linker increases the water solubility of the compound. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.