214487-45-3

中文名称 214487-45-3

英文名称 1H-Indole-3-carboxamide, N-[(1R,2S)-2-[[(2R)-2-[methyl[2-(4-methylphenyl)acetyl]amino]-3-(2-naphthalenyl)-1-oxopropyl]amino]cyclohexyl]-

CAS 214487-45-3

分子式 C38H40N4O3

分子量 600.749

MOL 文件 214487-45-3.mol

214487-45-3 结构式

基本信息物理化学性质图谱信息常见问题列表

基本信息

中文别名

化合物 T10056

英文别名

Neurokinin antagonist 1
1H-Indole-3-carboxamide, N-[(1R,2S)-2-[[(2R)-2-[methyl[2-(4-methylphenyl)acetyl]amino]-3-(2-naphthalenyl)-1-oxopropyl]amino]cyclohexyl]-

物理化学性质

沸点926.8±65.0 °C(Predicted)

密度1.26±0.1 g/cm3(Predicted)

储存条件-20°C储存

溶解度溶于二甲基亚砜

酸度系数(pKa)14.05±0.40(Predicted)

图谱信息

214487-45-3(214487-45-3)核磁图(¹HNMR)

常见问题列表

生物活性

Neurokinin antagonist 1是 Neurokinin 的拮抗剂，来自专利WO1998045262A1。

靶点

Neurokinin

体外研究

The invention in the patent WO1998045262A1 refers to antagonists of the interaction between the P substance and the NK-1 receptor, the process for their preparation, and their use in pharmaceutical compositions which may be used in the treatment of pathological forms in which the P substance receptor is involved, and in particular in the treatment of the inflammation of airways, such as asthma and rhinitis, and in the treatment of emesis.