217082-60-5
中文名称
人牛吡啶APELIN-13
英文名称
PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
CAS
217082-60-5
分子式
C69H108N22O16S
分子量
1533.8
MOL 文件
217082-60-5.mol
更新日期
2025/05/13 11:37:44
217082-60-5 结构式
基本信息
中文别名
人牛吡啶APELIN-13[PYR1]-爱帕琳肽-13
[PYR1]-爱帕琳肽-13, >98%
人,牛(GLP1)-APELIN-13肽
英文别名
Pyr-apelin-13[PYR1]-APELIN-13
(Glp1)-Apelin-13
[pGlu1]-Apelin-13
PYR-RPRLSHKGPMPF-OH
[PE]APELIN-13, HUMAN, BOVINE
(GLP1)-APELIN-13, HUMAN, BOVINE
(PYR1)-APELIN-13 (HUMAN, BOVINE)
[PGLU1]APELIN (24-36), HUMAN, BOVINE
(PYR1)-APELIN-13 (HUMAN, BOVINE, MOUSE, RAT)
所属类别
生物化工：多肽物理化学性质
密度1.51±0.1 g/cm3(Predicted)
储存条件Keep in dark place,Sealed in dry,Store in freezer, under -20°C
酸度系数(pKa)3.56±0.10(Predicted)
形态粉末
颜色White to off-white
水溶解性Soluble to 1 mg/ml in sterile water
序列Pyr-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH
人牛吡啶APELIN-13价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/02/08 | HY-P1033 | 人牛吡啶APELIN-13 [Pyr1]-Apelin-13 | 217082-60-5 | 1mg | 784元 |
| 2025/02/08 | HY-P1033 | 人牛吡啶APELIN-13 [Pyr1]-Apelin-13 | 217082-60-5 | 2 mg | 1254元 |
| 2025/02/08 | HY-P1033 | 人牛吡啶APELIN-13 [Pyr1]-Apelin-13 | 217082-60-5 | 5mg | 2600元 |
常见问题列表
生物活性
[Pyr1]-Apelin-13 是一种高效的，选择性的内源性 apelin 受体激动剂。体外研究
[Pyr1]-apelin-13 encapsulation in lipoPEG particles (lipoPEG-PA13) results in sustained and extended drug release under physiological conditions.
体内研究
[Pyr1]-apelin-13 nanocarriers in a mouse model of pressure-overload induced heart failure demonstrate a sustainable long-term effect of [Pyr1]-apelin-13 in preventing cardiac dysfunction. [Pyr1] apelin-13 (1, 5 μg) improves locomotor activity and reduces pain symptoms, cavity size and caspase-3 levels in rats. [Pyr1] apelin-13 (1, 5 μg) significantly increases thermal paw withdrawal latency. [Pyr1] apelin-13 in 5 μg dose also produces significant attenuation in paw withdrawal threshold compared to SCI animals from the second week post SCI.