2219324-71-5
2219324-71-5 结构式
物理化学性质
密度1.24±0.1 g/cm3(Predicted)
溶解度DMF: 20 mg/ml; DMF:PBS (pH 7.2) (1:5): 0.16 mg/ml; DMSO: 5 mg/ml
酸度系数(pKa)11.43±0.10(Predicted)
形态A crystalline solid
应用领域
用途一
BB-Cl-Yne is a cell-permeable derivative of the protein arginine deiminase (PAD) inhibitor BB-Cl-amidine that contains an alkyne moiety for use in click chemistry reactions. BB-Cl-Yne inhibits PAD1-4 and has been used for labeling PADs in cell-free and cell-based assays, followed by click reactions with azide-modified TAMRA or biotin reporters.