223769-64-0

中文名称羟基脒双(甲磺酸)

英文名称 HydroxystilbaMidine bis(Methanesulfonate) [Know as FluoroGold^(TM), TM of FluorochroMe]

CAS 223769-64-0

更新日期 2026/01/26 09:18:13

分子式 C17H20N4O4S

分子量 376.43

MOL 文件 223769-64-0.mol

223769-64-0 结构式

基本信息物理化学性质安全数据羟基脒双(甲磺酸)价格(试剂级) 常见问题列表

基本信息

中文别名

羟基脒双(甲磺酸)
羟芪巴脒*DNA和RNA染料*

英文别名

Fluoro-Gold
Hydroxystilbamidine *CAS 223769-64-0*
HydroxystilbaMidine bis(Methanesulfonate) [Know as FluoroGold(TM), TM of FluorochroMe]
4-[2-[4-(Aminoiminomethyl)phenyl]ethenyl]-3-hydroxybenzenecarboximidamide bis(methanesulfonate)
HydroxystilbaMidine bis(Methanesulfonate) [Know as FluoroGold^(TM), TM of FluorochroMe]

物理化学性质

储存条件2-8°C

溶解度可溶于水

形态粉末状

颜色Light yellow to yellow

InChI1S/C16H16N4O.2CH4O3S/c17-15(18)12-5-2-10(3-6-12)1-4-11-7-8-13(16(19)20)9-14(11)21;2*1-5(2,3)4/h1-9,21H,(H3,17,18)(H3,19,20);2*1H3,(H,2,3,4)/b4-1+;;

InChIKeyYGNSQKCULHSJDC-HFPMQDOPSA-N

SMILESCS(O)(=O)=O.CS(O)(=O)=O.NC(=N)c1ccc(cc1)\C=C\c2ccc(cc2O)C(N)=N

安全数据

危险性符号(GHS) GHS hazard pictograms

GHS07

警示词警告

危险性描述H315-H319-H335

防范说明P261-P264-P271-P280-P302+P352-P305+P351+P338

危险品标志Xi

危险类别码36/37/38

安全说明26-36

WGK Germany3

存储类别11 - Combustible Solids

危险性类别Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

羟基脒双(甲磺酸)价格(试剂级)

报价日期	产品编号	产品名称	CAS号	包装	价格
2025/12/22	HY-108166A	羟基脒双(甲磺酸) Hydroxystilbamidine bis(methanesulfonate)	223769-64-0	1 mg	850元
2025/12/22	HY-108166A	羟基脒双(甲磺酸) Hydroxystilbamidine bis(methanesulfonate)	223769-64-0	5 mg	2850元
2025/12/22	HY-108166A	羟基脒双(甲磺酸) Hydroxystilbamidine bis(methanesulfonate)	223769-64-0	10 mg	4500元

常见问题列表

生物活性

Hydroxystilbamidine bis(methanesulfonate) 是一种能够结合 DNA 和 RNA 的染料，也被发现是细胞核糖核酸酶的强效抑制剂。

体外研究

It is found that the trypanocidal dye Hydroxystilbamidine bis(methanesulfonate) permits the recovery of mRNA after polysome released with Nonidet P-40 (NP-40). Sucrose gradient analysis of detergent-lysed postnuclear supernates is used to analyze the size distribution of NP-40-released polysomes. The heparin gradient shows some polyribosomes, whereas the Hydroxystilbamidine bis(methanesulfonate) gradient shows a remarkably large peak of very heavy polyribosomes. This peak is obtained reproducibly if Hydroxystilbamidine bis(methanesulfonate) is present before the addition of NP-40.

体内研究

Hydroxystilbamidine bis(methanesulfonate) is an effective suppressor of the plaque-forming cell (PFC) response when given before sheep erythrocytes (SRBC) stimulation. Hydroxystilbamidine bis(methanesulfonate) depresses the plaque response of the treated mice. Fewer PFC are observed in Hydroxystilbamidine bis(methanesulfonate)-treated mice throughout the experiment, but the level of suppression decreases with time. By day 14, the number of PFC observed in both the Hydroxystilbamidine bis(methanesulfonate) treated mice and the control group is essentially at the background level.