247572-63-0
中文名称
Peptide C105Y
英文名称
Peptide C105Y
CAS
247572-63-0
更新日期
2025/09/28 10:17:51
分子式
C97H148N20O23S
分子量
1994.43
MOL 文件
247572-63-0.mol
247572-63-0 结构式
基本信息
中文别名
多肽C105YH-CYS-SER-ILE-PRO-PRO-GLU-VAL-LYS-PHE-ASN-LYS-PRO-PHE-VAL-TYR-LEU-ILE-OH
英文别名
C105YPeptide C105Y
Peptide C105Y、[Cys58]105Y, α1-antitrypsin (358-374)
L-Isoleucine, L-cysteinyl-L-seryl-L-isoleucyl-L-prolyl-L-prolyl-L-α-glutamyl-L-valyl-L-lysyl-L-phenylalanyl-L-asparaginyl-L-lysyl-L-prolyl-L-phenylalanyl-L-valyl-L-tyrosyl-L-leucyl-
物理化学性质
沸点2033.5±65.0 °C(Predicted)
密度1.275±0.06 g/cm3(Predicted)
酸度系数(pKa)3.41±0.10(Predicted)
序列Cys-Ser-Ile-Pro-Pro-Glu-Val-Lys-Phe-Asn-Lys-Pro-Phe-Val-Tyr-Leu-Ile
Peptide C105Y价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2023/03/20 | HY-P1781 | Peptide C105Y Peptide C105Y | 247572-63-0 | 5mg | 4000元 |
| 2023/03/20 | HY-P1781 | Peptide C105Y Peptide C105Y | 247572-63-0 | 10mg | 6800元 |
常见问题列表
生物活性
Peptide C105Y，基于 α1-抗胰蛋白酶 359-374 残基氨基酸序列合成的细胞穿透性肽，能增强 DNA 纳米粒的基因表达。体外研究
When human hepatoma cells (HuH7) were incubated with fluorescently labeled C105Y for as little as 3 min, C105Y displays nuclear and cytoplasmic staining with enrichment of fluorescent signal in the nucleus and nucleolus. C105Y peptide is routed to the nucleolus very rapidly in an energy-dependent fashion, whereas membrane translocation and nuclear localization are energy-independent. When tested the involvement of known endocytosis pathways in uptake and trafficking of this peptide, C105Y peptide is internalized by a clathrin- and caveolin-independent pathway, although lipid raft-mediated endocytosis may play a role in peptide intracellular trafficking.