247572-63-0
CAS
247572-63-0
更新日期
2024/06/03 09:46:34
247572-63-0 结构式
Peptide C105Y价格(试剂级)
报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
2023/03/20 | HY-P1781 | Peptide C105Y Peptide C105Y | 247572-63-0 | 5mg | 4000元 |
2023/03/20 | HY-P1781 | Peptide C105Y Peptide C105Y | 247572-63-0 | 10mg | 6800元 |
常见问题列表
生物活性
Peptide C105Y,基于 α1-抗胰蛋白酶 359-374 残基氨基酸序列合成的细胞穿透性肽,能增强 DNA 纳米粒的基因表达。体外研究
When human hepatoma cells (HuH7) were incubated with fluorescently labeled C105Y for as little as 3 min, C105Y displays nuclear and cytoplasmic staining with enrichment of fluorescent signal in the nucleus and nucleolus. C105Y peptide is routed to the nucleolus very rapidly in an energy-dependent fashion, whereas membrane translocation and nuclear localization are energy-independent. When tested the involvement of known endocytosis pathways in uptake and trafficking of this peptide, C105Y peptide is internalized by a clathrin- and caveolin-independent pathway, although lipid raft-mediated endocytosis may play a role in peptide intracellular trafficking.