32795-44-1
32795-44-1 结构式
基本信息
中文别名
乙酰卡尼乙酰普卡胺
乙酰卡因胺
酰普卡因胺
乙酰化-普鲁卡胺
N-乙酰普鲁卡因胺
N-乙酰基普鲁卡因胺
英文别名
acekainidacecainide
TIMTEC-BB SBB005970
N-ACETYLPROCAINAMIDE
n-acetyloprokainamid
N-ACETYLPROCAINAMIDE, 99+%
N-ACETYLPROCAINAMIDE USP/EP/BP
4-acetamido-N-(2-(diethylamino)ethyl)benzamide
4’-((2-(diethylamino)ethyl)carbamoyl)acetanilide
4’-((2-(diethylamino)ethyl)carbamoyl)-acetanilid
物理化学性质
熔点138-140 °C(lit.)
沸点500.0±35.0 °C(Predicted)
密度1.097±0.06 g/cm3(Predicted)
储存条件-20°C
溶解度可溶 1%，澄清，无色至淡黄色 (1N HCl)
酸度系数(pKa)14.54±0.46(Predicted)
Merck13,20
安全数据
警示词警告
危险性描述H315-H319-H335
危险品标志Xi
危险类别码36/37/38
安全说明26-36
危险品运输编号3249
WGK Germany3
RTECS号AE1974350
危险等级6.1(b)
包装类别III
常见问题列表
生物活性
N-Acetylprocainamide 是第三代抗心律失常剂，能够抑制 K+ 通道。靶点
K + channel
体外研究
N-Acetylprocainamide is a K + blocker. N-Acetylprocainamide decreases the tensions induced by K + and methacholine. The pIC 50 values for N-acetylprocainamide against the contractions induced by 0.3 and 1 μM methacholine are 2.80 ± 0.03 and 2.65 ± 0.02, respectively. And such a relaxant effect of N-Acetylprocainamide is inhibited by K + channel blockers. N-Acetylprocainamide shows no effect on Na + absorption or Cl - secretion.