35607-20-6
35607-20-6 结构式
基本信息
中文别名
阿夫立定 英文别名
AvridineCP-20961
2,2'-[[3-(Dioctadecylamino)propyl]imino]diethanol
2,2'-[[3-(Dioctadecylamino)propyl]imino]bisethanol
N,N-Dioctadecyl-N',N'-bis(2-hydroxyethyl)propanediaMine
N,N-dioctadecyl-N',N'-bis(2-hydroxyethyl)1,3-propanediamine
N,N-Dioctadecyl-N',N'-bis(2-hydroxyethyl)-1,3-diaminopropane
物理化学性质
熔点39-40°C
沸点717.6±40.0 °C(Predicted)
密度0.892±0.06 g/cm3(Predicted)
储存条件Store at RT
溶解度DMSO：≥5mg/mL（升温至 60°C 5 分钟）
酸度系数(pKa)14.41±0.10(Predicted)
形态粉末
颜色白色至灰白色
常见问题列表
生物活性
CP-20961 是有效的、合成的无免疫原性的、可诱导关节炎的佐剂。体内研究
Avridine-induced arthritis is severe and long lasting in LEW and DA rats.
CP-20961 (10 mg/kg, i.v., once either 24, 48, or 72 hours post-burn) had no effect on survival after challenge with
P. aeruginosa
96 hours post-burn.
| Animal Model: | Female, Hartley-derived guinea pigs, weighing 350 to 400 g. |
| Dosage: | 10 mg/kg. |
| Administration: | IV once either 24, 48, or 72 hours post-burn. |
| Result: | Had no effect on survival after challenge with P. aeruginosa 96 hours post-burn. |