39967-60-7
39967-60-7 结构式
基本信息
中文别名
脱氧假尿苷2'-脱氧假尿苷
英文别名
Deoxypseudouridine2'-DEOXYPSEUDOURIDINE
2'-Deoxypseudo-D-uridine
2,4(1H,3H)-Pyrimidinedione, 5-(2-deoxy-β-D-erythro-pentofuranosyl)-
5-(2-Deoxy-beta-D-erythro-pentofuranosyl)-2,4(1H,3H)-pyrimidinedione
物理化学性质
熔点220-222 °C(Solv: ethanol (64-17-5); methanol (67-56-1))
密度1.503±0.06 g/cm3(Predicted)
储存条件-20°C储存
溶解度DMSO : ≥ 37 mg/mL (162.14 mM)
酸度系数(pKa)8.52±0.10(Predicted)
常见问题列表
用途
脱氧假尿苷是一种有用的研究化合物。
生物活性
Deoxypseudouridine 是一种核苷酸类似物。体外研究
Deoxypseudouridine is a nucleotide analog. Ethidium bromide staining of the gel demonstrates that the digestion of carrier DNA in both control and analog DNA samples (including Deoxypseudouridine) occur to the same extent; this indicates that the restriction enzyme is as active in the presence of the modified DNA substrate (including Deoxypseudouridine) as it is in the presence of unmodified (control) DNA. Enzymes that do not contain an AT base pair in their recognition sequence, restrict DNAs substituted with either deoxypseudouridine or deoxytubercidin as efficiently as control.