480450-85-9
中文名称
依度沙班杂质49
英文名称
Acetic acid, 2-[[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]amino]-2-oxo-, ethyl ester
CAS
480450-85-9
分子式
C21H31N5O5S
分子量
465.57
MOL 文件
480450-85-9.mol
更新日期
2025/11/11 17:21:20
480450-85-9 结构式
基本信息
中文别名
依度沙班杂质65依杜沙班杂质70
依度沙班杂质49
2-(((1S,2R,4S)-4-(二甲基氨基甲酰基)-2-(5-甲基-4,5,6,7-四氢噻唑并[5,4-C]吡啶-2-甲酰胺基)环己基)氨基)-2-氧代乙酸酯(依度沙班杂质)
英文别名
Edoxaban Impurity 65Edoxaban Impurity 70
Edoxaban Impurity 49
Edoxaban Impurity 12 (1S, 2S, 4S)
ethyl 2-(((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)amino)-2-oxoacetate
Ethyl 2-(((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)amino)-2-oxoacetate (Edoxaban Impurity)
Acetic acid, 2-[[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]amino]-2-oxo-, ethyl ester
所属类别
分析化学：药典标准品和杂质标准品物理化学性质
密度1.32±0.1 g/cm3(Predicted)
储存条件Storage temp. 2-8°C
酸度系数(pKa)11.23±0.60(Predicted)
外观Off-white to yellow Solid
InChIKeyQKJLAWLACPRXCK-KCQAQPDRSA-N
SMILESC(OCC)(=O)C(N[C@H]1CC[C@H](C(N(C)C)=O)C[C@H]1NC(C1=NC2CCN(C)CC=2S1)=O)=O