51744-55-9

英文名称 15H-9,12-Imino-21,2-metheno-4,7:17,14-dinitrilopyrano[4,3-b]azacyclononadecine-16-propanoic acid, 10-ethenyl-5-ethyl-1,16,18,20-tetrahydro-6,11,15,22-tetramethyl-18,20-dioxo-, methyl ester, (15S,16S)-

CAS 51744-55-9

分子式 C34H34N4O5

分子量 578.67

MOL 文件 51744-55-9.mol

51744-55-9 结构式

基本信息物理化学性质常见问题列表

基本信息

英文别名

Purpurin 18 methyl ester
15H-9,12-Imino-21,2-metheno-4,7:17,14-dinitrilopyrano[4,3-b]azacyclononadecine-16-propanoic acid, 10-ethenyl-5-ethyl-1,16,18,20-tetrahydro-6,11,15,22-tetramethyl-18,20-dioxo-, methyl ester, (15S,16S)-

物理化学性质

熔点267 °C

沸点974.8±65.0 °C(Predicted)

密度1.271±0.06 g/cm3(Predicted)

常见问题列表

生物活性

Purpurin 18 methyl ester，叶绿素 a 的衍生物，是一种可用于光动力疗法 (PDT) 的光敏剂。Purpurin 18 methyl ester 具有光动力学活性，可诱导癌细胞死亡。

体外研究

Purpurin 18 methyl ester (1-5 μg/mL; 24 h) has no cytotoxicity in dark in HepG-2 cells.
Purpurin 18 methyl ester (1-5 μg/mL; 24 h) decreases the viability of HepG-2 cells in a concentration-dependent manner with irradiation for 10 min.
Purpurin 18 methyl ester (0-24 h) is released from GO- Purpurin 18 methyl ester (Pu18) composite, with rates of 47%, 22% and 30% in weak acidic condition (pH 5.6), neutral environment (pH 7.4) and weak alkali condition (pH 8.9) for 24 h, respectively.