53101-49-8
中文名称
(R)-(+)-6-羟基-2,5,7,8-四甲基色满-2-羧酸
英文名称
(R)-(+)-6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID
CAS
53101-49-8
分子式
C14H18O4
分子量
250.29
MOL 文件
53101-49-8.mol
53101-49-8 结构式
基本信息
中文别名
(R)-(+)-6-羟基-2,5,7,8-四甲基没-2-羧酸(R)-(+)-6-羟基-2,5,7,8-四甲基色烷-2-羧酸
(R)-(+)-6-羟基-2,5,7,8-四甲基色满-2-羧酸
英文别名
(R)-Trolox(R)-Trolox D5
Trolox (R)-Isomer
Trolox Impurity 1 (Trolox (R)-Isomer)
(R)-(+)-6-hydroxy-2,5,7,8-tetramethyl-chroman-2-C
(2R)-2,5,7,8-Tetramethyl-6-hydroxychroman-2-carboxylic acid
(R)-(+)-6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID
(R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid 98%
(R)-3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid
(2R)-6-Hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid
物理化学性质
熔点162 °C (dec.) (lit.)
沸点450.3±45.0 °C(Predicted)
密度1.219±0.06 g/cm3(Predicted)
储存条件-20°C储存
溶解度DMSO: 250 mg/mL (998.84 mM)
酸度系数(pKa)3.35±0.20(Predicted)
形态Solid
颜色White to off-white
旋光度 (Optical Rotation)[α]27/D +65°, c = 1.2 in ethanol
(R)-(+)-6-羟基-2,5,7,8-四甲基色满-2-羧酸价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/05/22 | HY-101445A | (R)-(+)-6-羟基-2,5,7,8-四甲基色满-2-羧酸 (R)-Trolox | 53101-49-8 | 50mg | 510元 |
| 2025/05/22 | HY-101445A | (R)-(+)-6-羟基-2,5,7,8-四甲基色满-2-羧酸 (R)-Trolox | 53101-49-8 | 10mM * 1mLin DMSO | 561元 |
| 2025/05/22 | HY-101445A | (R)-(+)-6-羟基-2,5,7,8-四甲基色满-2-羧酸 (R)-Trolox | 53101-49-8 | 100mg | 820元 |
常见问题列表
生物活性
(R)-Trolox 是水溶性维生素 E 类似物，是一种竞争性酪氨酸酶抑制剂，Ki 值为 0.83 mM，ID50 值为 1.88 mM。(R)-Trolox 具有比 (S) 对映异构体更强的酪氨酸酶亲和力 (Ki 值为 0.61 mM)。体外研究
As compared to the control containing no inhibitor, DMSO suppresses the tyrosinase activity at tested levels, 100 and 200 µL in a total volume of 3.0 mL. The inhibition of DMSO on the mushroom tyrosinase is dosedependent. Additions of DMSO at the two levels in the tyrosinase digests containing (R)-Trolox ((R)-HTCCA) results in further inhibitions of the tyrosinase activity. The influence of the DMSO on the inhibitory effects of (R)-Trolox against the tyrosinase is also dose-dependent.