57961-90-7
57961-90-7 结构式
基本信息
中文别名
化合物CENTHAQUINE 英文别名
PMZ-2010Centhaquin
Centhaquine
Centhaquin PMZ-2010
Centhaquin >=98% (HPLC)
Centhaquin (Centhaquine,PMZ-2010)
2-[2-[4-(3-Methylphenyl)-1-piperazinyl]ethyl]quinoline
Quinoline, 2-[2-[4-(3-methylphenyl)-1-piperazinyl]ethyl]-
Centhaquine价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/04/30 | HY-106690 | Centhaquine Centhaquin | 57961-90-7 | 5mg | 700元 |
| 2024/04/30 | HY-106690 | Centhaquine Centhaquin | 57961-90-7 | 10mM * 1mLin DMSO | 770元 |
| 2024/04/30 | HY-106690 | Centhaquine Centhaquin | 57961-90-7 | 10mg | 1200元 |
常见问题列表
生物活性
Centhaquine (Centhaquin) 是一种具有研究出血性休克的潜力的试剂。Centhaquine 在出血模型中可以减少全身血管阻力。体内研究
Centhaquine (Centhaquin) (intravenous injection, 0.01-1.0 mg/kg; intraduodenal administration 1.0-2.5 mg/kg) lowers the blood pressure and reduced the heart rate of anaesthetized and unanaesthetized (decerebrate) cat in a dose-dependent manner. Centhaquine (Centhaquin) (intravertebral arterial injection; 5-10 μg) or by topical application to the exposed ventral surface of medulla or floor of the fourth ventricle causes hypotension and bradycardia as well as reduced the excitability of the vasomotor loci. Centhaquine (Centhaquin;PMZ-2010) (intravenous administration; 0.015mg/kg) can attenuate the deleterious effects of catecholamines, improving both the macro- and microcirculation during CPR.
| Animal Model: | Landrace/Large White piglets |
| Dosage: | 0.015mg/kg |
| Administration: | Intravenous administration; Adrenaline 0.02mg/kg plus Centhaquin 0.015mg/kg |
| Result: | Added to adrenaline improved ROSC rates in a swine model of VF cardiac arrest. |