A 23887 (5S,4'R)-3-Chloro-10,11-dihydro-N,N-dimethylspiro[5H-dibenzo[a,d]cycloheptene-5,1'-[2]cyclohexen]-4'-amine [1S,4R]-3'-Chloro-10',11'-dihydro-N,N-dimethylspiro[2-cyclohexene-1,5'-[5H]dibenzo[a,d]cyclohepten]-4-amine
应用领域
用途一
A23887 is a potentially neuroleptic tetracyclic spiro amine that has affinity for dopamine D-2 receptors. It is important for defining the pharmacophore for D-2 antagonist activity due to its limited conformational freedom.
常见问题列表
概述
A 23887 是一种半刚性抗精神病化合物，对多巴胺 D2 受体 (dopamine D2 receptor) 具有相当大的亲和性。
