72957-42-7
中文名称
腺苷-5'-(Β,Γ-亚氨基)三磷酸四锂
英文名称
ADENYLYL-IMIDODIPHOSPHATE, TETRALITHIUM SALT
CAS
72957-42-7
分子式
C10H13Li4N6O12P3
分子量
529.93
MOL 文件
72957-42-7.mol
72957-42-7 结构式
基本信息
中文别名
腺苷酰基亚胺二磷酸四锂盐腺苷-5'-(Β,Γ-亚氨基)三磷酸四锂
英文别名
App(NH)pATP[β,γ-NH]
AMP-PNP, LI4
AMP-PNP, 4LI
biochemika90%
AMP PNP (~90%)
AMP-PNP LITHIUM SALT
AMP-PNP tetralithium
APP [NH]P LITHIUM SALT
AMP-PNP TETRALITHIUM SALT
物理化学性质
熔点>225°C (dec.)
储存条件−20°C
储存条件−20°C
溶解度H2O: 50 mg/mL
溶解度H2O:50 mg/mL
形态powder
颜色white
水溶解性26.5mg/ml in water
稳定性吸湿性
常见问题列表
生物活性
AMP-PNP tetralithium (Adenylyl-imidodiphosphate tetralithium) 是 ATP 不可水解的类似物，可抑制 KATP 通道。体外研究
AMP-PNP (5 to 500 μM; Li salt) reduced the open-probability p
o
of K
ATP
channels and decreases the single-channel currents at high nucleotide concentrations by approximately 10%.
AMP-PNP inhibits K
ATP
channels of ventricular myocytes and of pancreatic β-cells both in the absence and presence of Mg
2+
ions.