78103-18-1

中文名称 Methyl 2-Deoxy-D-erythro-pentopyranoside Bis(4-Methylbenzoate) (Decitabine IMpurity)

英文名称 Methyl 2-Deoxy-D-erythro-pentopyranoside Bis(4-Methylbenzoate) (Decitabine IMpurity)

CAS 78103-18-1

分子式 C22H24O6

分子量 384.42

MOL 文件 78103-18-1.mol

78103-18-1 结构式

基本信息应用领域

基本信息

英文别名

UKFSGKLSXCFJNM-UHFFFAOYSA-N
Methyl 2-Deoxy-D-erythro-pentopyranoside Bis(4-methylbenzoate)
D-erythro-Pentopyranoside, methyl 2-deoxy-, 3,4-bis(4-methylbenzoate)
Methyl 2-Deoxy-D-erythro-pentopyranoside Bis(4-Methylbenzoate) (Decitabine IMpurity)

应用领域

用途一

Methyl 2-Deoxy-D-erythro-pentopyranoside Bis(4-methylbenzoate) is an impurity of Decitabine (α-isomer: D226730), a DNA hypomethylating agent that is used to treat various forms of cancer, such as myelogeneous leukemia and metastatic lung cancerBy inhibiting DNA methyltransferase, Decitabine silences the tumour suppressor genes and, consequently, “normalizing” gene expression in cancerous cells.