796-42-9
796-42-9 结构式
基本信息
NSC51355
NSC-51355
NSC 51355
AS8351
AS 8351
NSC51355
NSC 51355
NSC-51355
N'-[(2-Hydroxy-1-naphthyl)methylene]isonicotinohydrazide
N'-((2-hydroxynaphthalen-1-yl)methylene)isonicotinohydrazide
N-[(Z)-(2-oxonaphthalen-1-ylidene)methyl]pyridine-4-carbohydrazide
N'-[(2-hydroxynaphthalen-1-yl)methylidene]pyridine-4-carbohydrazide
4-Pyridinecarboxylic acid, 2-[(2-hydroxy-1-naphthalenyl)methylene]hydrazide
物理化学性质
制备方法
54-85-3
708-06-5
796-42-9
H2La、H2Lb和H2Lc的合成采用标准方法：将等摩尔量的异烟酰肼（吡啶-4-甲酰肼）与相应的醛（5-溴-2-羟基苯甲醛、2-羟基-1-萘甲醛或2,4-二羟基苯甲醛）在乙醇中回流反应3小时，随后冷却至室温。通过缓慢蒸发化合物的稀乙醇溶液，获得适用于X射线晶体学分析的晶体。
参考文献：
[1] European Journal of Inorganic Chemistry, 2017, vol. 2017, # 6, p. 999 - 1006
[2] Polyhedron, 2014, vol. 79, p. 88 - 96
[3] Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2006, vol. 64, # 4, p. 853 - 858
[4] Medicinal Chemistry Research, 2014, vol. 23, # 1, p. 269 - 279
[5] Journal of the American Chemical Society, 1953, vol. 75, p. 5434
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/05/22 | HY-100744 | AS8351 AS8351 | 796-42-9 | 5mg | 495元 |
| 2025/05/22 | HY-100744 | AS8351 AS8351 | 796-42-9 | 10mM * 1mLin DMSO | 550元 |
| 2025/05/22 | HY-100744 | AS8351 AS8351 | 796-42-9 | 10mg | 700元 |
常见问题列表
KDM5B
AS8351 affects epigenetic modifications by competing with α-ketoglutarate (α-KG) for chelating iron [Fe(II)] in certain epigenetic enzymes, such as the JmjC domain-containing histone demethylases (JmjC-KDMs) that require α-KG and iron as co-factors.