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9072-41-7

中文名称 MOTILIN (HUMAN, PORCINE)
英文名称 MOTILIN (HUMAN, PORCINE)
CAS 9072-41-7
分子式 C120H188N34O35S
分子量 2699.05
MOL 文件 9072-41-7.mol
9072-41-7 结构式 9072-41-7 结构式

基本信息

英文别名
Motilin(pig)
MOTILIN (HUMAN, PORCINE)

物理化学性质

密度1.48±0.1 g/cm3(Predicted)
储存条件-20°C储存
溶解度DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: slightly; PBS (pH 7.2): 5 mg/ml
形态结晶固体
序列Phe-Val-Pro-Ile-Phe-Thr-Tyr-Gly-Glu-Leu-Gln-Arg-Met-Gln-Glu-Lys-Glu-Arg-Asn-Lys-Gly-Gln

应用领域

用途一
Motilin is a polypeptide hormone that stimulates gastric motility through release in the small intestine and into the general circulation during fasting. In isolated rabbit duodenal segments, porcine motilin (10 nM-1 μM) induced phasic contractions and acetylcholine release from enteric neurons (EC50 = 2.5 nM). Formulations containing motilin are used to increase gastrointestinal motility in patients with diabetic gastroparesis, often in combination with erythromycin , an antibiotic and agonist at the motilin receptor.

常见问题列表

概述
Motilin, human, porcine 是一种胃肠激素,在禁食和进食后或饮水时释放。Motilin, human, porcine 可促进人胃中的肠胆碱能活性,EC50 为 33 nM,并调节胃肠运动功能。
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