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911212-25-4

中文名称 911212-25-4
英文名称 Cefoselis (hydrochloride)
CAS 911212-25-4
分子式 C19H23ClN8O6S2
分子量 559.01
MOL 文件 911212-25-4.mol
911212-25-4 结构式 911212-25-4 结构式

基本信息

中文别名
盐酸头孢噻利
英文别名
Cefoselis (hydrochloride)

物理化学性质

储存条件-20°C储存
溶解度溶于二甲基亚砜
形态粉末

常见问题列表

生物活性
Cefoselis hydrochloride 是的第四代头孢菌素,是一种 β-内酰胺抗生素。Cefoselis hydrochloride 对多种革兰氏阳性和革兰氏阴性生物均表现出良好的活性。Cefoselis hydrochloride 可以透过血脑屏障。
体外研究

Cefoselis, a new parenteral cephalosporin, was active against clinical isolates of both gram-positive and gram-negative aerobic bacteria. The activity of Cefoselis was similar to that of cefpirome and cefepime and generally superior to that of ceftazidime. Cefoselis showed potent antibacterial activity against Hemophilus influenzae and Moraxella catarrhalis.Cefoselis was highly active against MSSA and MSCNS. Cefoselis was poor in the activity against MRSA,MRCNS,PRSP and Enterococcus faecalis,and no activity for Enterococcus faecium.

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